{"id":2996,"date":"2023-12-18T09:35:51","date_gmt":"2023-12-18T09:35:51","guid":{"rendered":"https:\/\/cancerprevention.qmul.ac.uk\/?p=2996"},"modified":"2024-02-16T11:17:25","modified_gmt":"2024-02-16T11:17:25","slug":"2023-christmas-reading-list","status":"publish","type":"post","link":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/2023\/12\/18\/2023-christmas-reading-list\/","title":{"rendered":"2023 Christmas Reading List"},"content":{"rendered":"\n
\"\"<\/figure>\n\n\n\n

Marking the end of another busy year for the Cancer Prevention Group, we have hand picked 15 of our published research highlights for your festive enjoyment (with group members in green<\/mark>).

Wishing our readers a rejuvenating Christmas break. We look forward to sharing more with you in 2024!<\/p>\n\n\n\n

Paper Title<\/span><\/strong> <\/td>Objective(s)<\/strong> <\/span><\/td>Journal<\/mark><\/em> & Authors<\/mark><\/span><\/strong> <\/td><\/tr>
Years of life lost due to cancer in the United Kingdom from 1988 to 2017<\/a> <\/td>A range of summary statistics are used to measure the impact of different cancers on society. This study investigated the application of Years of Life Lost (YLL) \u2013 a statistic placing greater weight on cancer deaths in younger individuals \u2013 in routine cancer statistics, using cancer mortality data from 1988 to 2017. <\/td>British Journal of Cancer<\/mark><\/em><\/strong>  <\/strong><\/mark>

Amar S Ahmad, Judith Offman<\/mark>, Christine Delon, Bernard V North<\/mark>, Jon Shelton, Peter Sasieni <\/mark> <\/td><\/tr>
Future cancer risk after urgent suspected cancer referral in England when cancer is not found: a national cohort study<\/a> <\/td>Following referral for investigation of urgent suspected cancer within the English National Health Service, 7% of referred individuals are diagnosed with cancer.  

This study aimed to investigate the risk of cancer occurrence within 1\u20135 years, following an initial finding of no cancer from an urgent suspected cancer referral.  <\/td>		Lancet Oncology<\/em> <\/mark> <\/mark><\/strong>

Suzanne E Scott, Carolynn Gildea, Brian D Nicholson, Ruth E Evans<\/mark>, Jo Waller<\/mark>, Debs Smith, Arnie Purushotham, Thomas Round   <\/td><\/tr>
Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy<\/a>  <\/td>This multi-centre randomised control trial sought to measure the effectiveness and safety of e-cigarettes as a smoking cessation method in pregnant females.

To do this, the effectiveness and safety of e-cigarettes in pregnancy was compared with that of nicotine patches. 1,140 pregnant daily smokers were randomised to receive either: an e-cigarette intervention, or nicotine patches. <\/td>		Health Technology Assessment<\/mark><\/strong><\/em>  

Dunja Przulj,\u202fFrancesca Pesola<\/mark>,\u202fKatie Myers Smith,\u202fHayden McRobbie,\u202fTim Coleman,\u202fSarah Lewis,\u202fChristopher Griffith,\u202fRobert Walton,\u202fRachel Whitemore,\u202fMiranda Clark,\u202fMichael Ussher,\u202fLesley Sinclair,\u202fEmily Seager,\u202fSue Cooper,\u202fLinda Bauld,\u202fFelix Naughton,\u202fPeter Sasieni<\/mark>,\u202fIsaac Manyonda,\u202fPeter Hajek  <\/td><\/tr>
Modelled mortality benefits of multi-cancer early detection screening in England<\/a>  <\/td>Blood-based, multi-cancer early detection (MCED) tests are capable of detecting a shared cancer signal from any site in the body, with a single, low false-positive rate. MCED screening could offer a key contribution to early cancer diagnosis. 
 
In this study, potential benefits of MCED screening were modelled through a natural history (\u2018interception\u2019) model, for estimating longer-term benefits to a cohort screened between ages 50-79 years. <\/td>		British Journal of Cancer<\/strong><\/em> <\/mark> 

Peter Sasieni<\/mark>,\u202fRebecca Smittenaar,\u202fEarl Hubbell,\u202fJohn Broggio,\u202fRichard D Neal,\u202fCharles Swanton <\/td><\/tr>
Managing an extension of screening intervals: Avoiding boom and bust in health care workloads<\/a>  <\/td>National-level cancer screening programmes continue to collect evidence on the costs and benefits of extending screening intervals. Extending screening intervals however bring with them the possibility of yearly variations in screening workload, making health service planning difficult. 

This study explored and compared three different screening extension scenarios, to build a better picture of how such variation could be diminished \u2013 and how any transitions might be successfully managed.  <\/td>		International Journal of Cancer<\/strong><\/em>  <\/mark>

Francesca Pesola<\/mark>,\u202fMatejka Rebolj<\/mark>,\u202fPeter Sasieni<\/mark>\u202f<\/sup> <\/td><\/tr>
Predictors of the experience of a Cytosponge test: analysis of patient survey data from the BEST3 trial<\/a>  <\/td>Barrett\u2019s Oesophagus, a precursor to oesophageal adenocarcinoma, can be diagnosed using a Cytopsponge cell collection device. The BEST3 trial investigated whether detection of Barrett\u2019s is created by using a Cytosponge-trefoil factor 3 (TFF3) test.  

This study sought to understand patients\u2019 experience of the Cytosponge, by identifying factors associated with least positive experiences. <\/td>		BMC Gastroenterology<\/mark><\/strong><\/em> <\/mark> 

Bhagabati Ghimire,\u202fRebecca Landy<\/mark>,\u202fRoberta Maroni,\u202fSamuel G Smith,\u202fIrene Debiram-Beecham,\u202fPeter Sasieni<\/mark>,\u202fRebecca C Fitzgerald,\u202fGreg Rubin,\u202fFiona M Walter,\u202fJo Waller<\/mark>,\u202fBEST3 Consortium, Judith Offman<\/mark>\u202f <\/td><\/tr>
A case-control study to evaluate the impact of the breast screening programme on breast cancer incidence in England<\/a>  <\/td>The English National Health Service Breast Screening Programme was first introduced in 1988. Subsequent improvements in diagnostic techniques and treatments have meant the need for up-to-date evaluation of the programme\u2019s benefits on risk of death from breast cancer. 

A London pilot case-control study previously indicated a 39% mortality reduction from mammography screening. This study sought to evaluate the benefits England-wide, looking at women aged 47-89 years who died of primary breast cancer in 2010 or 2011. <\/td>		Cancer Medicine<\/mark><\/strong><\/em>  

Roberta Maroni,\u202fNathalie J Massat,\u202fDharmishta Parmar,\u202fAmanda Dibden,\u202fJack Cuzick,\u202fPeter Sasieni<\/mark>,\u202fStephen Duffy <\/td><\/tr>
Widening the offer of human papillomavirus self-sampling to all women eligible for cervical screening: Make haste slowly<\/a>  <\/td>Self-collection of samples for human papillomavirus (HPV) testing has the potential to increase the uptake of cervical screening among under-screened women. With self-sampling becoming increasingly available in high-income settings, it is important to evaluate the benefits and drawbacks of a wider move to cervical self-sampling. 

This review looked at the current evidence around the \u2018early-adopter\u2019 programme, to determine how well (and consistently) thresholds relating to uptake and detection sensitivity were being met.  <\/td>		International Journal of Cancer<\/mark><\/em><\/strong> <\/strong><\/mark> 

Matejka Rebolj<\/mark>,\u202fAlexandra Sargent,\u202fSisse Helle Njor,\u202fKate Cuschieri <\/td><\/tr>
Awareness and knowledge about HPV and primary HPV screening among women in Great Britain: An online population-based survey<\/a>  <\/td>Cervical cancer screening via human papillomavirus (HPV) primary testing is now being implemented on a global scale.  

This study explored HPV awareness, together with knowledge about primary screening, in Great Britain, ahead of extended screening intervals being introduced in England. <\/td>		Journal of Medical Screening<\/mark><\/em> <\/strong> 

Jo Waller<\/mark>, Frances Waite<\/mark>, Laura AV Marlow<\/mark> <\/td><\/tr>
The impact of age-relevant and generic infographics on knowledge, attitudes and intention to attend cervical screening: A randomized controlled trial<\/a>  <\/td>With cervical screening uptake rates falling in England, it is important to evaluate multiple evidence-based avenues to attempt to remedy this. Infographics are one such avenue. The offer the potential to strengthen intention to attend, increase positive attitudes and improve knowledge. Age targeting could improve these outcomes further.  

This study tested the impact of both generic and age-targeted infographics on intentions, knowledge and attitudes related to cervical screening, among women aged 25-64 (n = 2,095). <\/td>		British Journal of Health Psychology<\/mark><\/strong><\/em>  

Frances Waite<\/mark>,\u202fLaura AV Marlow<\/mark>,\u202fMartin Nemec,\u202fJo Waller <\/mark><\/td><\/tr>
Unpacking the Lay Epidemiology of Cervical Cancer: A Focus Group Study on the Perceptions of Cervical Cancer and Its Prevention among Women Late for Screening in Norway<\/a>  <\/td>Non-attendance for cervical cancer screening is commonly understood in terms of a knowledge deficit: as a lack of \u2018appropriate\u2019 or \u2018correct\u2019 knowledge of disease risks and prevention. Few studies have explored lay interpretations of cervical cancer to date. 

This study addressed how cervical cancer epidemiology and prevention is interpreted among \u2018lay\u2019 individuals, among women late for cervical cancer screening in Norway. <\/td>		Healthcare<\/em> <\/mark><\/strong> 

Gunvor Aasb\u00f8,\u202fBo T Hansen,\u202fJo Waller<\/mark>,\u202fMari Nyg\u00e5rd,\u202fKari N Solbr\u00e6kke <\/td><\/tr>
Exploring the psychosexual impact and disclosure experiences of women testing positive for high-risk cervical human papillomavirus<\/a>  <\/td>This study explored the psychosexual impact and disclosure experiences of women testing HPV-positive following cervical screening. Via interviews with 21 women of screening age in England (aged 24-65 years), the nature and impact of disclosure experiences on women\u2019s current, past and future interpersonal and sexual relationships were explored.  <\/td>British Journal of Health Psychology<\/strong><\/em> <\/mark> <\/mark>

Kirsty F Bennett,\u202fJo Waller<\/mark>,\u202fJulia V Bailey,\u202fLaura AV Marlow<\/mark>        <\/td><\/tr>
Do age-targeted messages increase cervical screening intentions in women aged 50-64\u202fyears with weak positive intentions? A randomised control trial in Great Britain<\/a>  <\/td>Over 20% of women aged 50-64 in Britain have not attending cervical screening within the recommended 5-year interval.  

This study aimed to investigate the impact of five messages on the strength of intention to attend, in women aged 50-64 with weak positive screening intentions for their next invitation.  <\/td>		Preventive Medicine<\/mark><\/strong><\/em>  

Frances\u202fWaite<\/mark>,\u202fLaura AV\u202fMarlow<\/mark>,\u202fMartin\u202fNemec,\u202fJo\u202fWaller<\/mark>  <\/td><\/tr>
Psychological\u202fImpact of the\u202fGalleri test (sIG(n)al): protocol for a longitudinal evaluation of the psychological impact of receiving a cancer signal in the NHS-Galleri trial<\/a>\u202f <\/td>This protocol outlines a proposed project embedded in the NHS-Galleri trial, a large clinical trial of a multi-cancer early detection (MCED) blood test, across eight Cancer Alliances in England.  

The project aims to explore the psychological impact of having a cancer signal detected following a MCED blood test. The project looks at anxiety as the primary outcome for determining psychological impact, alongside psychological consequences of screening, reassurance\/concern about the test result, understanding of results and help-\/health-seeking behaviours. <\/td>		BMJ Open<\/strong><\/em>  <\/mark>

Laura AV Marlow<\/mark>, Ninian Schmeising-Barnes<\/mark>, Jane Warwick,\u202fJo Waller <\/mark><\/td><\/tr>
Lung adenocarninoma promotion by air pollutants<\/a> <\/td>This study sought to address the limited understanding of how environmental exposures promote cancer formation. Specifically, it looked at particulate matter (PM2.5<\/sub> \u2014 air pollutant particles) and their association with lung cancer. In doing so, it also revisited a 70-year-old theory of tumorigenesis, building a more complex picture of the multi-layer cellular events ultimately leading to cancer development.  <\/td>Nature<\/mark><\/strong><\/em> 
 
William Hill,\u202fEmilia L Lim,\u202fClare E Weeden,\u202fClaudia Lee,\u202fMarcellus Augustine,\u202fKezhong Chen,\u202fFeng-Che Kuan,\u202fFabio Marongiu,\u202fEdward J Evans Jr,\u202fDavid A Moore, Felipe S Rodrigues,\u202fOriol Pich, Bjorn Bakker,\u202fHongui Cha,\u202fRenelle Myers,\u202fFebe van Maldegem,\u202fJesse Boumelha, Selvaraju Veeriah,\u202fAndrew Rowan,\u202fCristina Naceur-Lombardelli,\u202fTakahiro Karasaki,\u202fMonica Sivakumar,\u202fSwapnanil De,\u202fDeborah R Caswell,\u202fAi Nagano,\u202fJames RM Black,\u202fCarlos Mart\u00ednez-Ruiz,\u202fMin Hyung Ryu,\u202fRyan D Huff,\u202fShijia Li, Marie-Julie Fav\u00e9,\u202fAlastair Magness,\u202fAlejandro Su\u00e1rez-Bonnet,\u202fSimon L Priestnall,\u202fMargreet L\u00fcchtenborg,\u202fKatrina Lavelle,\u202fJoanna Pethick,\u202fSteven Hardy,\u202fFiona E McRonald,\u202fMeng-Hung Lin,\u202fClara I Troccoli,\u202fMoumita Ghosh, York E Miller,\u202fDaniel T Merrick,\u202fRobert L Keith,\u202fMaise Al Bakir, Chris Bailey,\u202fMark S Hill,\u202fLao H Saal,\u202fYilun Chen,\u202fAnthony M George,\u202fChristopher Abbosh,\u202fNnennaya Kanu,\u202fSe-Hoon Lee,\u202fNicholas McGranahan,\u202fChristine D Berg,\u202fPeter Sasieni<\/mark>,\u202fRichard Houlston,\u202fClare Turnbull,\u202fStephen Lam,\u202fPhilip Awadalla, Eva Gr\u00f6nroos, Julian Downward,\u202fTyler Jacks,\u202fChristopher Carlsten,\u202fIlaria Malanchi,\u202fAllan Hackshaw,\u202fKevin Litchfield,\u202fTRACERx Consortium, James DeGregori,\u202fMariam Jamal-Hanjani, Charles Swanton <\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

.<\/h2>\n\n\n\n

The views expressed are those of the author. Posting of the blog does not signify that the Cancer Prevention Group endorses those views or opinions.<\/em><\/p>\n\n\n\n

Subscribe to our mailing list!<\/strong><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Marking the end of another busy year for the Cancer Prevention Group, we have hand picked 15 of our published research highlights for your festive enjoyment (with group members in green). Wishing our readers a rejuvenating Christmas break. We look forward to sharing more with you in 2024! Paper Title  Objective(s)  Journal & Authors  Years… Read More »2023 Christmas Reading List<\/span><\/a><\/p>\n","protected":false},"author":3,"featured_media":3008,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"neve_meta_sidebar":"","neve_meta_container":"","neve_meta_enable_content_width":"","neve_meta_content_width":0,"neve_meta_title_alignment":"","neve_meta_author_avatar":"","neve_post_elements_order":"","neve_meta_disable_header":"","neve_meta_disable_footer":"","neve_meta_disable_title":"","cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[4,6,7,483,8,9,12,14,30,37,38,42,57],"tags":[],"class_list":["post-2996","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-air-pollution-and-lung-cancer-series","category-behavourial-science","category-bowel-screening","category-brain-cancer","category-breast-cancer","category-breast-screening","category-cancer-prevention","category-cervical-cancer","category-edi","category-hpv-screening","category-hpv-self-sampling","category-lung-cancer","category-reading-list"],"_links":{"self":[{"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/posts\/2996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/comments?post=2996"}],"version-history":[{"count":16,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/posts\/2996\/revisions"}],"predecessor-version":[{"id":3069,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/posts\/2996\/revisions\/3069"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/media\/3008"}],"wp:attachment":[{"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/media?parent=2996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/categories?post=2996"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cancerprevention.qmul.ac.uk\/index.php\/wp-json\/wp\/v2\/tags?post=2996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}